South Dakota

Population: 853,175
State Rank: 46
Funding By State: 
AgencyFunding (in thousands)State Rank
National Institutes of Health$21,35245
Centers for Disease Control and Prevention$16,550 47
National Science Foundation$22,40342
Agency for Healthcare Research and Quality$0 38
Total$60,30546
Economic Impact: 
IndustryEmploymentAnnual Salary
Pharmaceutical14$41,769
Medical Device1,631$55,681
Research, Testing, and Laboratories422$85,687
Overall Private Sector5,175$36,316
Source: 

Battelle and Biotechnology Industry Organization (BIO), Battelle/BIO State Bioscience Jobs, Investments and Innovation, 2014

Investment: Funding Sources: 
Source of R&D Funding InvestmentState Rank
Federal Government$110,000,00050
Industry$99,000,00046
Universities$20,000,00050
Total $229,000,00049
Notes: 

*Note that the total does not include estimates for philanthropic funding. Philanthropic funding, including that by voluntary health organizations, is not available on a state by state basis.

Source: 

National Science Foundation, Science & Engineering Indicators, 2014

The capabilities are enormous, a little bit of research can pay off quite a bit in the long run.
Paul D’ Addario, retinitis pigmentosa patient