Alzheimer’s

As the Chief Science Officer of the Alzheimer’s Drug Discovery Foundation (ADDF), I am often asked: what is drug discovery? It is the “innovation engine” that drives breakthroughs in treating diseases. Diseases of the brain, such as Alzheimer’s, are complex. Though the cause of Alzheimer’s isn’t fully understood, scientists continue to uncover new processes that contribute to it. And each new finding into the cause of the disease represents a potential target for drugs to treat it – and an opportunity for innovation. When the ADDF was founded in 1998, the pipeline of drugs in development for Alzheimer’s was limited. The few drugs being developed almost all focused on the same target, beta-...
“Though we’ve been gloried in success, we still have unfinished business” when it comes to tackling cardiovascular disease, said NHLBI Director Dr. Gary Gibbons, highlighting the findings of a new American Heart Association-commissioned analysis at an event in Washington, D.C. last week. The report presented data on what lies ahead in cardiovascular disease prevalence and costs over the next few decades. Projections found more than 131 million people – or about 45 percent of the U.S. population – could suffer from cardiovascular disease by 2035, and annual costs related to this – both direct medical costs and lost productivity – could surpass $1 trillion; that’s more than all other chronic...
Dear Research Advocate, The President’s signature on hard fought funding and tax legislation was enough to end the year on a high note, but there’s more good news: In an interview on C-SPAN , Senate HELP Committee Chairman Lamar Alexander (R-TN) said what many of us have been waiting to hear: “Number one, what we want to turn our attention to [in 2016] is what we call the Innovation Bill.” After the 21st Century Cures pay-fors were used to help offset lost revenues in the FY16 Omnibus/Tax package, the prospects for mandatory NIH and FDA funding seemed weak. However, not only did Chairman Alexander reiterate his support for mandatory funding, but House Energy and Commerce Committee Chairman...

Sidebar Quote

America’s economic destiny lies in innovation, technology, science and research.
The Honorable John E. Porter