As the Chief Science Officer of the Alzheimer’s Drug Discovery Foundation (ADDF), I am often asked: what is drug discovery? It is the “innovation engine” that drives breakthroughs in treating diseases. Diseases of the brain, such as Alzheimer’s, are complex. Though the cause of Alzheimer’s isn’t fully understood, scientists continue to uncover new processes that contribute to it. And each new finding into the cause of the disease represents a potential target for drugs to treat it – and an opportunity for innovation. When the ADDF was founded in 1998, the pipeline of drugs in development for Alzheimer’s was limited. The few drugs being developed almost all focused on the same target, beta-...

Sidebar Quote

Without continued support for health research, many of the most promising young scientists, their ideas and a myriad of potentially life-changing scientific breakthroughs will vanish into oblivion.
Paul Marinec, PhD; University of California San Francisco